[Scientific temperature] Born with ＂explosive head＂, is this suffering from ＂Puffy syndrome＂？

　　BEIJING, Beijing, October 25 (Wei Xianghui) In life, people who are born with "explosive heads" can easily attract people’s attention. In fact, this may be a genetic disease related to genes, which is medically called puffiness syndrome, and is also vividly called "difficult to comb hair syndrome". Doctors said that in general, such diseases have little impact on patients’ health, but they look different from ordinary people in appearance, and the lives of some patients may be troubled.

　　Girls don’t want to go to school because they are born with "explosive heads"

　　Recently, a 6-year-old girl from Cao County, Heze City, Shandong Province, was unwilling to go to school because she was teased by her classmates because of her natural hair and explosive hairstyle.

　　The girl’s mother, Ms. Cheng, told Zhongxin. com that her and her husband’s hair was normal, and the girl’s brother didn’t have any hair, but only the girl’s grandfather’s hair was slightly curly at home. When her daughter was over 1 year old, Ms. Cheng was worried about her health problems and took her to the hospital for examination. The doctor said that the girl’s physical examination index is normal, and her unkempt hair may be inherited from the next generation.

　　Some netizens said that the girl’s hair is unkempt, which is similar to the hairstyle of the late scientist Albert Einstein. The girl may have a rare "puffy hair syndrome".

　　For "Puffy syndrome", Ms. Cheng has never heard of this concept from a doctor. Zhangfan, director of the beijing jishuitan hospital Hair Research Center, told Zhongxin. com that from the video, girls’ hair has the typical appearance characteristics of "Puffy Hair Syndrome", but genetic testing is still needed to confirm the diagnosis.

　　The actual patient is higher than the confirmed record.

　　Zhangfan introduced that Puffy Syndrome is an autosomal dominant genetic disease. From the appearance characteristics, the hair is dry and curly, and it is difficult to comb. "Puffy hair syndrome" is usually found in early childhood. The patient’s hair does not grow downward, but grows in many directions from the scalp.

　　It is found that there are three genes that may be closely related to the disease: PADI3, TGM3 and TCHH. These three genes are all related to hair: PADI3 is found to be mainly expressed in hair follicles, and the enzyme produced can modify hair shafts; TGM3 is a transglutaminase, which can act on hair protein. TCHH plays a role in the inner root sheath of hair follicle together with PADI3.

　　According to Xinhua News Agency, Washington post quoted the National Institutes of Health as saying that Puffy Hair Syndrome is a rare hair gene mutation disease. Usually, the symptoms of patients are obvious between 3 months and 12 years old, and the patients’ hair is curly, dry and light in color, which makes it impossible to comb. Einstein is believed to be a patient with herpes simplex syndrome. At this stage, there are only 100 such cases in the United States.

　　Zhangfan said that although there are few recorded confirmed cases, once the "Puffy Syndrome" has symptoms, it may be passed on to the next generation, so the actual number of patients may exceed the number of confirmed cases.

　　Proper nursing can improve hair quality.

　　At present, Ms. Cheng’s daughter is still not sure that she has "Puffy Syndrome", but she told Zhongxin.com that her child was also troubled by hairstyle problems at school: "My daughter is in the first grade this year, and her classmates laughed at her. When she came back, she asked me, ‘ Mom, why did you give me such hair? I’m not going to school. ’”

　　Some netizens encouraged the little girl in the comment area and praised her unique hairstyle. Even, some netizens shared their similar experiences. "I am this kind of hair. I have been laughed at since I was a child, and I can understand her feelings. Although adults also feel good-looking, I still have to understand the feelings of children and find ways to help them solve problems."

　　"Generally speaking, ‘ Puffy syndrome ’ It will not affect your health. " Zhangfan said that because people’s nerves and skin system organs originated from the same germ layer, hair diseases may be complicated with other developmental abnormalities. For example, with ectodermal dysplasia, patients will not only show hair problems, but also may have mental retardation. She said that if the patient’s other development is normal, it may be just an abnormality of hair keratin.

　　She suggested that if someone is troubled in life, they can do basic care for their hair, such as proper use of hair mask and essential oil, so as to supplement structural protein and improve hair quality. (End)