2023 edition of influenza vaccination handbook

Recently, a new strain has appeared in COVID-19.

According to the evaluation of the World Health Organization on August 9th, the mutant EG.5 shows the characteristics of enhanced transmission ability and immune escape ability.

If there is a peak in November in the future, it is very likely to form mixed infection with this year’s influenza virus.

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The World Health Organization (WHO) has released the candidate strains of seasonal influenza vaccine in the northern hemisphere in 2023-2024, and our influenza vaccine has also arrived this year.

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Components of tetravalent chicken embryo culture vaccine:

A/Victoria/4897/2022 (H1N1) PDM09-like virus

A/Darwin/9/2021 (H3N2)-like virus

B/Australia/1359417/2021 virus (B/Victoria pedigree)

B/Phuket/3073/2013-like virus (B/Yamagata lineage)

Tetravalent cell culture or recombinant protein vaccine components:

A/Wisconsin/67/2022(H1N1)pdm09-like virus

A/Darwin/6/2021 (H3N2)-like virus

B/Australia/1359417/2021 virus (B/Victoria pedigree)

B/Phuket/3073/2013-like virus (B/Yamagata lineage)

Components of trivalent chicken embryo culture vaccine:

A/Victoria/4897/2022 (H1N1) PDM09-like virus

A/Darwin/9/2021 (H3N2)-like virus

B/Australia/1359417/2021 virus (B/Victoria pedigree)

Trivalent cell culture or recombinant protein vaccine components:

A/Wisconsin/67/2022(H1N1)pdm09-like virus

A/Darwin/6/2021 (H3N2)-like virus

B/Australia/1359417/2021 virus (B/Victoria pedigree)

Now that the flu vaccine is in place, let’s talk about the flu virus and this year’s flu vaccine.

1. How terrible is the flu? Why do you suggest vaccination?

Influenza (influenza for short) is an acute respiratory infectious disease caused by influenza virus. It is spread by airborne droplets and people are generally susceptible, and influenza can kill people.

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A considerable number of people don’t take the flu seriously, thinking that it is just a slightly worse cold.

In fact, the seasonal epidemic of influenza every year can lead to 3-5 million severe cases and 290,000-650,000 deaths worldwide. The annual influenza attack rate of adults in the world can reach 5%-10%, and that of children is as high as 20%.

This means that in the high season of influenza, one in every 10 adults is infected with influenza; One out of every five children will get the flu. And influenza will break out every 10-40 years, causing serious health and economic burden.

For example, in the United States, on average, 36,000 people die of influenza every year, which is more than deaths caused by alcohol or traffic accidents. As far as the United States is concerned, the annual economic losses caused directly or indirectly by the flu are as much as $7 billion.

In recent years, the incidence and mortality of influenza in China have shown a steep upward trend. According to the data of China Center for Disease Control and Prevention, in the first five months of 2019 alone, the number of reported cases of influenza reached 1.77 million, exceeding the total number of reported cases of influenza in the past four years.

In the past February and March of 2023, the positive rate of influenza virus detection exceeded 25.1%, forming a large-scale epidemic.

Vaccination against influenza every year is the most effective means to prevent influenza, which can significantly reduce the risk of influenza and serious complications. Therefore, WHO suggests that people should be vaccinated every year to prevent influenza and its complications.

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However, in China, the importance of influenza vaccine has not been fully recognized by the whole society. Influenza vaccine is a self-funded "non-immunization program vaccine" with a low vaccination rate.

Second, how to vaccinate to prevent influenza virus more effectively?

1. Inoculate every year

Influenza virus is easy to mutate. In order to match the ever-changing influenza virus, the influenza vaccine recommended by the World Health Organization will update one or more strains in most seasons, and the vaccine strains are exactly the same as those in the previous epidemic season.

In order to ensure the maximum protection of the vaccinated population, even if the composition of influenza vaccine is exactly the same as that of the previous epidemic season, considering that the immunity of most vaccinators will gradually weaken over time, influenza vaccine still needs to be vaccinated every year.

2. Inoculate in advance

Clinically, the season in which influenza occurs most often varies according to different regions. In China, the annual cycle of influenza changes with the increase of the latitude of the earth. Generally, it is more prevalent in the northern provinces above 33 degrees north latitude, with the peak in January and February every year, and the southernmost provinces south of 27 degrees north latitude have the peak in April and June every year. In the mid-latitude areas between the two, there are two very obvious flu peaks every year.

Usually after 2-4 weeks of influenza vaccination, antibodies with protective level can be produced. Therefore, it is recommended to vaccinate the influenza vaccine 1-2 months before the peak of influenza epidemic every year, so as to effectively play the protective role of the vaccine.

3. Inoculation on demand

Besides trivalent and tetravalent influenza vaccines, there are also three types of influenza vaccines: children, adults and general vaccines, and even the vaccination methods are different. You can choose the most suitable seasonal influenza vaccine for vaccination according to your own situation.

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Three, ten hot issues of influenza vaccine

1. How many shots should the flu vaccine take every year?

It depends on age:

Children and adults aged 9 and above:Only one dose is needed;

Children aged 6 months to 8 years:Children aged 6 months to 8 years who are vaccinated for the first time or have been vaccinated with influenza vaccine below 2 doses in the past should be vaccinated with 2 doses, with an interval of ≥4 weeks; Children who have been vaccinated with 2 or more doses of influenza vaccine before are recommended to be vaccinated with 1 dose.

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2. Can I get the flu vaccine if I am allergic to eggs or milk?

In all authoritative documents and guidelines at home and abroad, people who are allergic to eggs are not considered as taboos for influenza vaccination.

In fact, if you are allergic to any food, you can get the flu vaccine normally. There is no need to confirm whether you are allergic to a certain food before vaccination. If you have allergic symptoms that require urgent medical intervention after eating eggs, such as anaphylactic shock, it is recommended to vaccinate in medical institutions that identify and manage serious allergic diseases.

3. Who really can’t get the flu vaccine?

Those who are allergic to the ingredients contained in the vaccine include excipients, formaldehyde, Triton X-100, etc. Other people with severe allergies; Those with a history of Guillain-Barre syndrome; Patients with uncontrolled epilepsy and other progressive neurological diseases.

In addition, critically ill patients with various diseases should be used with caution; Patients with acute fever, acute infection and acute attack of chronic diseases should be vaccinated after recovery. For different kinds of vaccines from different manufacturers, the vaccination contraindications listed in the instructions are slightly different. Please refer to the vaccine instructions for details.

Special attention should be paid to the contraindications of live attenuated influenza vaccine.(At present, only nasal spray influenza is an attenuated live vaccine listed in China):

① Persons with low immune function due to drug use, HIV infection and other reasons;

② Children and adolescents who have been treated with drugs containing aspirin or salicylic acid for a long time;

③ Children with asthma aged 2-4 years;

4 pregnant women;

⑤ Patients with Guillain-Barre syndrome (GBS) history;

⑥ Those who used antiviral drugs such as oseltamivir and zanamivir 48 hours before inoculation, or those who used palamivir 5 days before inoculation, or those who used balofloxacin 17 days before inoculation.

4. Will you still get the flu after the flu vaccine?

This is possible, because the virus circulating in some areas may not be the influenza virus contained in the vaccine. In addition, it should be noted that influenza vaccine can only prevent influenza, but not the common cold at the same time.

5. Is it necessary to have an interval of more than one year between influenza vaccination and last year’s influenza vaccination?

"Vaccination every year" does not mean that this year’s influenza vaccination time must be a whole year apart from last year’s. Accurately speaking, the "year" here refers to "every flu season that spans natural years".

The influenza vaccine of the current season will be listed before the epidemic season of that year, and it can usually be vaccinated in August and September, and the validity period will end in March of the following year. That is to say, the flu vaccine given in August and September of that year was the same batch as that given before March of the following year. The flu vaccine in August and September of the following year is the next epidemic season.

Then, if you were vaccinated in August and September of that year, you don’t need to be vaccinated in March of the following year. On the contrary, if you were vaccinated before March of the following year, you still need to be vaccinated in August and September of the following year. There is no saying that the interval must be one year, mainly depending on whether the vaccine you are vaccinated belongs to the season.

6. Can people who have had the flu within one year get the flu vaccine?

Having a history of influenza in the past is not a taboo for vaccination. In addition, influenza viruses are prone to mutation, so it is possible to prevent influenza viruses prevalent in the current season by vaccination. Therefore, vaccination is still needed.

7. Can I get a flu vaccine during pregnancy and lactation?

A large number of studies at home and abroad have confirmed that "pregnant women have a higher risk of severe illness, death and adverse pregnancy outcome after suffering from influenza", that is, if pregnant women are infected with influenza virus, it may bring serious harm to both the fetus and themselves.

Therefore, pregnant women should be vaccinated against influenza more than others. And pregnant women can be vaccinated with inactivated influenza vaccine at any stage of pregnancy. If you are pregnant or plan to be pregnant during the flu season, you should get the flu vaccine.

Under the premise of the instructions, lactating women can also be vaccinated with influenza vaccine, and they can breastfeed normally after vaccination.

8. What is the difference between different influenza vaccines?

At present, there are trivalent inactivated influenza vaccine (IIV3), tetravalent inactivated influenza vaccine (IIV4) and trivalent attenuated live vaccine (LAIV3) that have been approved for marketing, among which IIV3 includes split vaccine and subunit vaccine, and IIV4 is split vaccine, and attenuated vaccine is the nasal spray vaccine mentioned earlier.

The difference between inactivated vaccine and attenuated live vaccine is that the former does not contain active virus components while the latter contains attenuated virus components. They can all trigger the immune response of the human body.

In addition, at present, the inactivated and attenuated influenza vaccines listed in China are inoculated in different ways: the inactivated vaccine is intramuscular injection, and the attenuated live vaccine is intranasal spraying.

The difference between trivalent and tetravalent is that the latter has one more pedigree of influenza B than the former (which can be simply understood as preventing one more strain of influenza B virus), and there is no difference in the preventive effect of influenza A contained in the latter. All of them can be inoculated to prevent influenza, and there is no priority recommendation, that is, when the vaccine is available, whatever is used can be chosen voluntarily according to their own conditions.

9. There is a scheduling conflict between influenza vaccine and other vaccines. Which vaccines can be vaccinated at the same time?

Inactivated influenza vaccine, other inactivated vaccines and attenuated live vaccines, such as pneumococcal vaccine, live attenuated herpes zoster vaccine, varicella vaccine, measles vaccine and DTP vaccine, can be inoculated in different parts at the same time;

After vaccination with live attenuated influenza vaccine, other live attenuated influenza vaccines can only be vaccinated after an interval of more than 28 days;

Older people over 65 can be vaccinated with influenza vaccine and pneumococcal vaccine at the same time.

Other special provisions shall be subject to the vaccine instructions of specific manufacturers.

10. After taking antibiotics and antiviral drugs, how long will it take to get the flu vaccine?

There is no taboo to get flu vaccine after antibiotic use.

However, taking influenza antiviral drugs 48 hours before vaccination is not recommended (it can be vaccinated after 48 hours).

Although there are a few very small and low-quality literature reports that taking antibiotics may reduce the immune response of influenza vaccine, it is not clear whether this has clinical significance or not, and it has not yet become a consensus.

But then again, if you are taking medicine, the high probability is that you are unwell or even in the acute stage of the disease, then it is recommended to suspend vaccination. At least wait until the symptoms improve and the condition is stable, or consider vaccination after stopping taking medicine.

References:

[1]World Health Organization. Fact sheeton influenza(seasonal).In. [http://www.who.int/en/news-room/fact-sheets/detail/influenza-(seasonal)].

[2] Gong Zhenyu, Gong Xunliang. WHO’s recommendation on the composition of influenza vaccine virus strains used in the northern hemisphere during the influenza season from 2023 to 2024 [J]. Preventive Medicine, 2023,35 (05): 460. DOI: 10.19485/J.CNKI.ISSN 2096-5087.

[3] China Center for Disease Control and Prevention. The national epidemic situation of legal infectious diseases in .http://www.nhc.gov.cn/jkj/s2907/new_list.shtml? tdsourcetag=s_pcqq_aiomsgaccessed July,2019.

[4] Technical Guidelines for Influenza Vaccination in China (2022-2023).

[5] Liu Xiaoxue, Song Yifan, Zhang Zhaonan, et al. Analysis on the coverage of influenza vaccine estimation report in China in 2014-2021 [J]. China Journal of Viral Diseases, 2023,13 (03): 226-232. DOI: 10.16505/J.2095-0136.

[6]Hagan et al. Antibiotics-Driven Gut Microbiome PerturbationAlters Immunity to Vaccines in Humans. 2019, Cell 178, 1313–1328. full text:https://www.cell.com/cell/fulltext/S0092-8674(19)30898-0

Write | Liu Xiao

Proofreading | Gddra

Editor | Hide/Blue sea

Edit Design | Alice

Come and Pick the new director, and the 1 billion box office debut opportunity is in your hands.


Special feature of 1905 film network This may be the first time that Xiao Dianjun has been looking forward to the summer vacation since graduation.

 

Why should I ask? The reason is simple, this summer’s movies are worth looking forward to! In two words, it is "wonderful"!

 

You don’t believe me? Xiao Dianjun will analyze it for you.

 

I believe that the first thing on many people’s must-see list is — — Ok.

Not to mention the joining of the powerful actors, the word "Director Jiang Wen" alone is "sexy" enough, not to mention that Eddie Peng Yuyan randomly shows an eight-pack abdominal muscle, which can be said to be quite "attractive".

When Xiao Dianjun interviewed the screenwriter Li Fei before, he learned that the style of this film would be closer. When "Let Bullets Fly" was released in 2010, it won 636 million box office and became the champion of Chinese movie box office that year.

Nowadays, "Evil Doesn’t Suppress Righteousness" is released in summer, and the box office ambition is directed at 1 billion. As for whether it can replicate last year’s market performance, this is also what everyone is paying attention to.

 

Of course, there is definitely more than one Chinese film directed at the box office of 1 billion.

 

Tsui Hark’s "Di Renjie" series will return again! To tell the truth, this series is Xiao Dianjun’s personal favorite Chinese commercial film, and Xu Laoguai has been trying to play various new film techniques in recent years. Even so, the plot content can guarantee enough wonders.

However, I sincerely hope that the Andy Lau version of Di Renjie will return at an early date.

 

The first two works in this series won 286 million box office and 600 million box office respectively. Previously, it was shown in the National Day file, and this time the re-election is in the summer file. I wonder if the results will be by going up one flight of stairs.

These two works have been sharpened by famous directors for many years, which has given Xiao Dianjun infinite expectations.

 

It’s just a pity that Xiao Dianjun got reliable news that Zhang Yimou’s new work originally planned for summer release may be postponed for a while. However, in the first notice released a while ago, it looks very good.

The old man abandoned the "big dye vat" this time. I don’t know what surprise it will bring to the audience.

 

In addition to the works of the above-mentioned veteran directors, Xiao Dianjun’s must-see list also includes a wave of works from "new people".

 

Don’t underestimate the performance of "new people", because Jason Wu was still a new director when he made Wolf Warriors 2. Generally speaking, to see the possibility of a director, we must first look at their first three works.

Therefore, Xiao Dianjun Pick up the works of four new directors for everyone. Whoever can win the 1 billion debut depends on everyone’s choice.

 

These four works are very topical before they are officially released, which is no less than the popularity of other films. However, now it seems that the popularity rankings of these films are a little unexpected for Xiao Dianjun.

As can be seen from the above table, Bo Huang’s works, which were originally thought to be grounded and recognized by the public, will have a high popularity. As a result, except for the popularity of Douban in The Island, the data of the other two ticketing platforms are not ideal.

 

It seems that Mr. Bo Huang’s pre-suspense-style propaganda has not sunk well into the third-and fourth-tier cities. But even so, Xiao Dianjun still thinks that it will be a late-stage force and become a dark horse in this summer’s file.

Unexpectedly, two works with relatively low popularity in Douban have high popularity on other platforms. Especially, when it is difficult for more and more people to have confidence in the quality of this sentimental movie, it can still earn the expectations of many viewers through "ten years of feelings".

 

So, which newcomer can have the last laugh this summer? Xiao Dianjun once again turned on the magic stick mode and had a few words with you.

 

Dying to Survive

Competitors:,

Possibility of explosion point: 75%

 

At first glance, our schedule is the safest of the four films at present. At present, there are 4 movies scheduled for July 6th, and only "Grand Prix 2" will have a certain impact on it. Of course, Animal World, which was released a week earlier, still poses a relative threat to it.

Han Yan directed Mangai’s works again. Although the style is different, according to the insiders, Animal World is better this time. It can be seen that it is still very possible for a long time to reach the second week.

 

At the same time, after the box office and word-of-mouth losses of the first series, the overall performance was flat.

 

Although TFBOYS are gathered in the cards of "Grand Prix 2", as far as Xiao Dianjun knows, more fans of the three little ones don’t pay the bill. It seems that this most critical purchasing power will be discounted. The first film finally closed at 382 million box office. Now it is still one month away from the release, and the publicity is far from as hot as the previous film. Therefore, we have to draw a question mark here to maintain the box office performance of the first film.

On the contrary, from the very beginning, Dying to Survive grasped the two trump cards of Xú Zhēng and Ning Hao. Especially for Xú Zhēng, this is his third producer work this year. The first two producer works (and) have accumulated more than 1.1 billion box office, which has been recognized by many audiences in terms of word of mouth.

With a solid foundation in the early stage, the audience will naturally have confidence in this work.

 

Not only that, Ning Hao also joined hands as producer. It is worth noting that this work is the second work in the "72 Change Movie Plan" launched by Bad Monkey Film in Ning Hao. The first work was released last summer. What’s important is that the word "Ning Hao" has always been the guarantee of business and word of mouth, and the films directed by myself have proved the strength of its input-output ratio again and again.

Now Dying to Survive has officially started the road show mode. Although the whole film has not been shown publicly for the time being, we can feel from the 40-minute footage exposed during the road show that the quality of the film will be guaranteed.

Moreover, in this movie, Cass used powerful actors. In the feedback of watching movies on campus in the early stage, many viewers not only praised Xú Zhēng’s performance frequently, but also specifically mentioned Eric Wang’s performance. Here, Xiao Dianjun digress, Eric Wang has become more and more immortal in recent years, and his role as a "messenger" in the movie can be described as very arresting. After that, I was not afraid of being set up by others, and I became a different person in the entertainment circle. I hope this work can help you to know the actor Eric Wang, not Sekitani Kamiki.

However, in terms of subject matter, compared with the comedies before Xú Zhēng and Ning Hao, Dying to Survive’s work is adapted from a true story, which seems to be more social realism. Therefore, whether it can attract more audiences into the cinema like comedies in the past is also the key to its long-term sales.

Next Page: The Richest Man in Xihong City, The Island and ipartment.

Brandon kleiner joined "End with Us" to cooperate with Blake.

Brandon kleiner

Brandon kleiner

     On April 27th, Beijing time, according to foreign media reports, Brandon kleiner (1923 and westworld) joined the new film End with Us, starring with Blake Lively and justin baldoni (Five Feet at the End of the World and Love Song on the Cloud).

  Berduni is also a director, adapted from Colleen Hoover’s best-selling novel, written by Christie Hall (Not What I Want) and produced by Sony.

  Lily (Lively), a small town girl who tells that life is not always smooth, strives for the life she wants. After graduating from college, she moves to Boston to start her own career. She sparks with Lyle (Berduni), a neurosurgeon who is handsome, charming, talented, stubborn and arrogant, and has a special liking for Lily.

  The relationship between the two fell into crisis with the reappearance of Lily’s first love Atlas (kleiner). Lily has long missed Atlas, who is her guardian. They share the same interests and have an unforgettable past. In the face of new people and old feelings, how does Lily choose?

  (Meng Qing)

After visiting Costco in China, Japan, South Korea and the United States, consumers say so …

  Shanghai Costco supermarket. Photo courtesy of consumers

  Recently, it was reported that Costco’s first store in Shanghai experienced a phenomenon of centralized queuing to return membership cards after its customers were full. What kind of experience is shopping in Costco? Yangzi Evening News reporters interviewed consumers who had had shopping experience in Costco supermarkets in Shanghai, Japan, South Korea and the United States respectively, and invited economists to talk about the phenomenon of card withdrawal in Costco Shanghai stores.

  Experienced by: Mr. Fu

  Shopping: Costco, China.

  Maotai was sold out long ago, and the price of Wuliangye increased.

  Mr. Fu, a Nanjing consumer, happened to be on a business trip in Shanghai recently. On the evening of September 5th, he went to Costco Supermarket with friends who had membership cards. "Moutai has long been sold out; Wuliangye has also increased its price, more than 1,000 yuan a bottle; Hermes bag can’t be seen either. However, roast chicken is still hot. " Mr. Fu introduced that his most intuitive feeling is that there are many young people in the whole Costco supermarket, mainly consumers aged around 20-40.

  "Like a large warehouse, shelves like IKEA." Mr. Fu introduced that his friend read the recommendation online, knew what was cheaper, and bought a bottle of red wine and a bag of potato chips. He feels that if he wants to buy something cheap, he’d better do his homework in advance. Some foreign-made things are really relatively cheap. He took photos of several commodity prices, and his friends said they were cheap. For example, 25ml or 30ml of Chloe and BOSS perfume costs 399 yuan a bottle. Levi’s jeans cost 429.9 yuan. According to friends, they usually cost around 600 yuan.

  "There are still many people, but they are orderly." According to Mr. Fu, when checking the card at the entrance, it was quite strict, and it was an electronic card. Most people come to the supermarket as a family.

  Mr. Fu said that because he went at night, he didn’t see the queue to return the card. The normal checkout channel still has to queue up around 9 pm.

  Experienced by: Mr. Lin

  Shopping: Costco, Japan

  Go shopping and have a PARTY when you get home.

  Mr. Lin, a consumer in Nanjing, lived in Japan before 2018. He told the Yangzi Evening News reporter that he had a membership card in Costco supermarket at that time, and the price was 4,400 yen, which was less than the RMB in 300 yuan (1,000 yen was about the RMB in 60 yuan). Japanese supermarkets are generally few and fine, while Costco supermarkets are full of American style and large quantity, which is very cheap on average.

  "Buy a trip, and you can have a PARTY when you go home." Mr. Lin introduced that Costco supermarkets are generally located in the suburbs. He lives in the center of Tokyo, 16 kilometers to the south, 40 kilometers to the east and about 50 kilometers to the west from several Costco supermarkets. Generally, family shopping is once every 1-2 weeks. Sushi is in a big box, with 48 pieces in a box, and 12 pieces in Japanese supermarkets. Roasted chicken is also popular in Japan, with a price of 699 yen. You should take the number before Christmas to buy roast chicken. Salmon and pork are also very cheap. Take pork ribs as an example, a large box is only 1800 yen. The most popular thing for children is a large jar of cashew kernel, which sells for 2,400 yen.

  Clothes are also sold very cheaply, such as jeans like Levi’s, which cost about 4,000 yen and are of good quality. He also bought ski clothes and glasses for his children, and bought his own black cotton-padded clothes for 4,000 yen/piece. Before returning to China, he didn’t see any luxury goods sold in Costco supermarket in Japan.

  Experienced by: Ms. Yan

  Shopping: Costco, Korea

  I basically didn’t see the phenomenon of card withdrawal.

  Ms. Yan, a Nanjing native who once lived in Daejeon, South Korea, told the Yangzi Evening News reporter that she had set up a membership card at the local Costco supermarket through a friend’s introduction. She spent 45,000 won on a membership card, which was converted into RMB less than 300 yuan (at that time, 1,000 won was equivalent to 6 yuan RMB).

  Ms. Yan introduced that she felt that the items sold in this supermarket were very rich. She has been there several times and bought bread, beef, eggs, milk, vegetables and other foods. "The food is fresh and full of weight." Ms. Yan recalled that there are also some luxury goods on sale in the supermarket.

  Ms. Yan said that she basically didn’t see the phenomenon of card withdrawal, probably because the positioning of this supermarket is more in line with the needs of the middle class.

  Experienced by: Ms. Yang

  Shopping: Costco, USA

  In 2016, I haven’t seen luxury goods yet.

  Ms. Yang, a citizen of Nanjing, spent more than 20 days in San Francisco, USA in 2016. At that time, she went shopping in Costco supermarket with friends with membership cards. When she traveled to the United States again in 2017, she lived in a homestay all the way. She usually went to an ordinary supermarket to buy daily necessities. Because of these two comparisons, she was deeply impressed by the cheap prices of goods in Costco supermarket.

  "Praise bread, $4.99, 3 dozen 36. A box of Butterfly Crisps is $4.99, 4 dozen 48 pieces. We drove in the west of the United States and didn’t eat all the way. Hershey’s chocolate and coffee are all sold by the package, and each package is more than one kilogram. Starbucks coffee beans are 2.5 pounds and more than ten dollars. " Ms. Yang introduced that this supermarket is suitable for family use because everything it sells is large. She found that if you buy the same product with similar total price in other supermarkets, the amount may be only half that of Costco supermarket.

  She remembers that Costco supermarkets in the United States are generally relatively large, about the size of IKEA or slightly smaller, mainly selling daily necessities such as food, clothing and use, as well as electrical appliances. But I don’t remember selling luxury goods at that time. (Yangzi Evening News/Yangyan reporter Merry ma Xu Wei Fu Yijie Intern Tao Meizhen)

After hot pot and mutton kebabs, mala Tang has also become popular in South Korea.

  "This dish is spicy, okay?" When I go to a restaurant in Korea, the boss often asks such questions after discovering that the author is Chinese. At first, I was curious why I asked, but after living in Korea for a long time, I found that "Chinese doesn’t eat spicy food" seems to be the "consensus" of many restaurant owners and waiters.

  Interestingly, Mala Tang, an out-and-out "Chinese food", suddenly caught fire in South Korea, and the "consensus" of Koreans on "Chinese doesn’t eat spicy food" is changing because of the popularity of Mala Tang. South Korea’s "Central Daily News" recently published a news report saying that Mala Tang has been sought after in South Korea in recent one or two years, and even promoted the sales of China beer in South Korea together with China’s mutton kebabs.

  Two years ago, most Koreans didn’t know what mala Tang was. Almost all of a sudden, several mala Tang restaurants appeared in business districts such as Myeongdong and Hongda. At that time, the author was so excited to eat mala Tang in a foreign country that he shared the address of mala Tang shop with other friends in China as if it were a treasure. Later, something unexpected happened. Mala Tang restaurants have mushroomed and exploded. How much is it now? There is a short alley downstairs in the author’s house. Only in this alley, there are three mala Tang shops.

  Nowadays, there are not only a large number of mala Tang shops in Seoul, but also many shops are getting bigger and bigger, and more and more branches are opened, forming a certain scale. One day, when I was watching TV, I found that the mala Tang restaurant downstairs appeared in an advertisement inserted by a famous Korean TV station. A search on the Internet revealed that this mala Tang restaurant has branches all over Korea, with more than 50 outlets in the capital circle alone, exclaiming that "the original online celebrity store is downstairs".

  Korean mala Tang restaurant, the decoration style is generally very simple, and the boss and employees are mostly Chinese. Although it is called Mala Tang Store, many stores are Mala Tang and spicy incense pot. There are all kinds of meat and dishes in the store for customers to choose and weigh. When making, you can choose to make it spicy or spicy. There are also many shops that offer other China stir-fried dishes and cold salad dishes as auxiliary dishes.

  In terms of taste, Mala Tang restaurants in South Korea have made some adjustments due to the limited variety of ingredients and catering to the tastes of Koreans. Although Chili or Chili powder is generally added to Korean diet, Korean food is relatively mild in spicy taste, and spicy pepper is not used in Korean traditional diet. Therefore, the spicy food, spicy incense pot and spicy pot in hot pot restaurant eaten in Korea are slightly different from those in China.

  When you think about it carefully, it’s not surprising that Mala Tang has spread all over Korea, because before it, many Chinese foods have been on fire. Speaking of Chinese food which is sought after in Korea, Zhajiang Noodles is the originator. At the end of the Qing Dynasty, overseas Chinese introduced Zhajiang Noodles to South Korea, and made localization improvement and opened noodle shops. Today, more than a hundred years later, Zhajiang Noodles has become a part of Korean daily diet. Incheon also has a Zhajiang Noodles Memorial Hall dedicated to this period of history. After the establishment of diplomatic relations between China and South Korea in 1992, Chinese hot pot and mutton kebabs became popular in South Korea, and now it’s Mala Tang’s turn.

  In fact, the introduction of Chinese food into South Korea is itself a product of non-governmental exchanges between the two countries and a microcosm of the history of bilateral relations. With the development of China and the deepening of foreign exchanges, there will be more and more non-governmental exchanges between China and South Korea in the future, and the people of the two countries will gain more understanding and friendship because of "eating".

1 billion! Spider-Man: No Return of Heroes became the global box office champion in 2021.


1905 movie network news Recently, Marvel Comics’s new film is being released around the world. Up to now, the global box office of the film has reached 1.05 billion US dollars, reaching the top of the global box office list in 2021, becoming the first film to break the box office of 1 billion US dollars in the epidemic era.


The strong box office performance of "Spider-Man: No Return of Heroes" not only brought unparalleled carnival enjoyment to fans, but also made the global cinema industry see the confidence of reviving. In the United States, a number of large chain cinemas have achieved the best ticket sales since then, and the chief executive officer of IMAX, Ricky Geffen, said, "Spider-Man: No Return of Heroes" shows us the signal of global cinema industry recovery.


The box office has been rising all the way, and the reputation of the film is not to be outdone. Rotten tomatoes started with 100% freshness, and 100% popcorn index reached the top of the year, creating the highest score record for rotten tomatoes scored by over 20,000 certified users. IMDb 9.0 was ranked 8th among the best 250 films, and CinemaScore was awarded A+ honor, making it the best evaluation in the history of Spider-Man live-action movies.


At the same time, the domestic platform Douban scored as high as 8.1, making it the superhero movie with the highest annual score. The story, performance, emotion and picture of the film have been fully affirmed by the audience, fans, film critics and professional media, and it has become the most eye-catching and popular superhero blockbuster in the epidemic era.


The film "Spider-Man: No Return of Heroes" was directed by Jon Watts again, and all the original cast members, such as,, and, returned and joined heavily. The film production has been upgraded in an all-round way, the super-strong lineup has been assembled, and the top-level special effects scenes have been presented, which is being shown around the world.


Students of Anhui Automobile Industry School Open the Road of "Work-study Alternation" to Break Cocoons and Become Butterflies

"Integration of production and education and alternation of work and study" is the concrete embodiment of implementing the spirit of the National Vocational Education Conference, and it is also an important measure to push forward the reform of vocational education. At the beginning of the new semester, Anhui Automobile Industry School selected two enterprises, namely Hefei Gree Electric and Weilai Automobile, as the work and study alternation enterprises of industrial robot specialty and new energy automobile specialty in 2020, on the basis of previous visits and on-the-spot investigation, and according to the principle of "professional counterparts and seeking truth from practice".

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Under the joint arrangement of schools and enterprises, nearly 300 students went to Hefei Gree Electric and Weilai Automobile for a four-month on-the-job teaching practice from September 5th. "It is the first time for many students to leave campus for a short time and experience the first line of enterprise production, and it is the key to do a good job in logistics service and on-the-job management." Li Liancheng, director of the Academic Affairs Office, who is in charge of leading the organization of work-study alternation, said that the school and the enterprise jointly set up a management working group. Not only did teachers live with students 24 hours a day, but also the school party Committee established a "guarantee system" for party Committee members to contact classes, and at the same time effectively played the role of the head teacher as a link to do a comprehensive and meticulous job.

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From September 6th, the students who participated in the work-study alternation passed the enterprise physical examination one after another, went through the entry formalities and got the "employee card" of the enterprise. "At present, everyone is a dual identity, that is, students at school and employees of enterprises. Enterprises have carried out pre-job safety training, corporate culture training and practical operation training." When talking about "dual management", Liang Zhuotao, director of the Student Affairs Office, said, "School management is the same as daily school attendance, quantitative assessment of dormitory hygiene, careful registration of students who take leave, strict implementation of the requirements of enterprises and territories for epidemic prevention and control, and good nucleic acid detection and prevention.

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On September 13th, it was the first day for the students of this school to officially take up their posts in Weilai Automobile. The school and the enterprise jointly held a "ceremony to learn from the teacher" for the students. The apprentices lined up in neat rows and bowed deeply to the master, took up the teacups and respectfully offered tea to the master. The master gave a speech and a gift to the apprentices. Fan Guangcheng, deputy director of the Admissions Office, said, "The ceremony marks the beginning of on-the-job teaching practice. At the same time, it also injects more sense of ceremony into school-enterprise cooperation by inheriting excellent traditional culture, so that both teachers and apprentices can conclude more sense of mission and responsibility."

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On-the-job teaching cannot be divorced from humanistic care. This year’s Mid-Autumn Festival is the first festival for students to leave home and campus for the enterprise. On the day of the festival, Wang Kun, secretary of the Party Committee and president of the school, and Shou Peicong, vice president of the school, visited the students in the enterprise, listened to their demands, learned about the accommodation and working environment, distributed holiday gifts to the students and spent the Mid-Autumn Festival with them. According to the arrangement, the school will regularly organize cultural and sports activities, patriotism education and excellent traditional culture education to keep abreast of students’ psychological trends and ensure that every student enjoys learning, thinking and making progress in the enterprise.

At present, the work-study alternation has been going on for more than half a month, and the students have all changed from "excitement" at the beginning to "adaptation" at present. The new job requirements, real practical operation and strict double norms have made the students of this school "break the cocoon into butterflies" and strive to move towards higher and stronger goals.

This work-study alternation arrangement has both theoretical training and productive practice. Students go deep into actual jobs, participate in productive labor, cultivate students’ professional skills and practical ability, acquire real workplace skills, consolidate knowledge, cultivate professional ability and enhance employment competitiveness in practice. (Liu Hai special correspondent: Chen Rong)

Sold 216,600 yuan, Dongfeng Yipai e π 008 officially listed

  [Autohome new car listing] On June 14th, Dongfeng Yipai eπ 008 () was officially launched.The new car launched a total of 2 models.The price is 216,600 yuan.The new car is positioned as a medium and large SUV, with extended-range hybrid models and pure electric models. The highlights of the new car include a 6-seat layout, providing "refrigerators, color TVs, large sofas", and a design similar to the new power style. The new car will be delivered within June. In addition, a number of car purchase rights were announced at the press conference, and the limited-time rights price of the new car is 188,600 yuan.

Dongfeng Yipai e π 008 guide price Model Selling price (10,000 yuan) 210 Max Extended Range Edition 21.66 636 Max pure electric version 21.66

汽车之家

汽车之家

汽车之家

汽车之家

汽车之家

东风乘用车 eπ008 2024款 纯电 基本型

东风乘用车 eπ008 2024款 纯电 基本型

  In terms of appearance, Dongfeng Yipai Eπ 008 adopts a minimalist design similar to new power models. The front face adopts through-type headlights, equipped with hidden intelligent star grilles, and when the daytime running lights are lit, it adopts a three-point design, which is relatively novel. There is a lot of white space on the entire front face, and the front enclosure retains the air inlet and diversion groove.

东风乘用车 eπ008 2024款 纯电 基本型

东风乘用车 eπ008 2024款 纯电 基本型

  On the side of the body, the new car pays more attention to the creation of space. It can be seen that the size of the front and rear doors is not small. It adopts a short front and rear overhang and a large wheelbase design. At the same time, the new car uses hidden door handles and multiple spoke wheels. In terms of body size, the length, width and height of the new car are 5002/1972/1732mm, and the wheelbase is 3025mm. In addition, the new car is equipped with 21-inch Continental silent tires.

东风乘用车 eπ008 2024款 纯电 基本型

东风乘用车 eπ008 2024款 纯电 基本型

  The rear of the vehicle is also a through-type taillight, the style is equally chic and impressive, the entire rear looks quite full, heavy, and the overall atmosphere is simple. The new car drag coefficient is 0.268.

东风乘用车 eπ008 2024款 纯电 基本型

东风乘用车 eπ008 2024款 纯电 基本型

汽车之家

汽车之家

  In terms of interior design, it is also simple. There are a lot of leather wraps in the car, which is a bit similar to the style of the ideal model. At the same time, the center console has wood grain decoration and chrome decoration. The new car provides a floating instrument panel and a large floating central control screen. The central control area of the car no longer retains physical buttons. The new car also provides streaming media rearview mirrors, double-layer laminated sound insulation glass, 50W wireless fast charging and 64-color ambient lights.

东风乘用车 eπ008 2024款 纯电 基本型

东风乘用车 eπ008 2024款 纯电 基本型

东风乘用车 eπ008 2024款 纯电 基本型

汽车之家

汽车之家

  The car offers a variety of apps, including Bilibili, Kuaishou, Sing Bar, Tencent Video, Douban Reading, etc. The overall interface of the car is relatively simple, the layout is reasonable, and the overall operation interface is similar to the ∞ style. Two wireless charging panels are provided under the central control screen, and there is a storage box at the rear. The new car is also equipped with a 20-speaker brand stereo.

汽车之家

东风乘用车 eπ008 2024款 纯电 基本型

东风乘用车 eπ008 2024款 纯电 基本型

汽车之家

东风乘用车 eπ008 2024款 纯电 基本型

汽车之家

汽车之家

东风乘用车 eπ008 2024款 纯电 基本型

东风乘用车 eπ008 2024款 纯电 基本型

  The new car adopts a 6-seat layout of 2 + 2 + 2. The second row provides electric seats, independent armrests, small table boards, car refrigerators, etc. At the same time, the car refrigerator can be moved back and forth. The rear row also provides a foldable 15.6-inch screen that can play videos or Karaoke. Due to the screen, the new car adopts a front and rear segmented sunroof design. The third row of seats is not too thin. After the back of the third row of seats is reclined, the trunk can form a flat storage space, and the new car trunk is equipped with an electric tailgate. The pure electric model also has a large-sized front trunk.

东风乘用车 eπ008 2024款 纯电 基本型

东风乘用车 eπ008 2024款 纯电 基本型

东风乘用车 eπ008 2024款 纯电 基本型

东风乘用车 eπ008 2024款 纯电 基本型

东风乘用车 eπ008 2024款 纯电 基本型

汽车之家

汽车之家

汽车之家

汽车之家

汽车之家

  动力方面,增程车型将搭载1.5T涡轮增压发动机作为增程器,发动机最大功率108千瓦,最大扭矩210牛·米,其搭载中创新航的磷酸铁锂电池组,驱动电机最大功率200千瓦,最大扭矩340牛·米,CLTC纯电续航210km,CLTC综合续航1300km,馈电油耗4.7L/100km,快充时间0.43小时。纯电动车型单电机最大功率200千瓦,最大扭矩340牛·米,采用东昱欣晟的磷酸铁锂电池组,CLTC续航里程636km,快充时间0.47小时。此外,新车配备了高速NOA领航辅助功能和超视距记忆泊车功能。

● 竞争对手:

星途 星纪元 ET 2024款 增程 200 Pro

『星途星纪元 ET』

  eπ008的主要竞争对手是星途星纪元 ET,其同样是采用类似于新势力风格的新能源车型,包括增程式混动和纯电车型,不过星纪元 ET是一款5座版车型,eπ008则是一款6座版车型,更注重后排空间的营造,“冰箱、彩电、大沙发”是它的优势所在。同时,这款车型配置齐全,有足够的产品竞争力。

● 编辑点评:

  东风奕派eπ008与星途星纪元 ET一样,是一款主打性价比的产品,其20万元左右的售价可以买到一款配置齐全的中大型SUV,并且产品配置也是相当卷。eπ007开了一个好头,5月份销量3032台,表现中规中矩,相信随着知名度的不断提升,后续销量还会有新的提升。eπ008上市后,其定位更加明确清晰,将会吸引相当一部分家庭用户的注意力,这款比理想更卷的车型,预计会有不错的销量表现。(文/汽车之家 秦超)

Safety must be the first priority. Let’s talk about the safety performance of Wuling Binguo.

In the traditional cognition of many consumers, the safety of small cars, especially small pure trams, is very general. However, with the technological upgrading and the technological leading edge of China car companies in new energy, the safety performance of pure electric cars is no less than that of hundreds of thousands or even millions of luxury cars, such as this one to be talked about today, which has made great efforts in safety.

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The proportion of ultra-high strength steel is 74%, and the body strength is quite excellent?

Many people think that small cars are unsafe, and most of them think that the body strength and body rigidity of small cars are average, but is Wuling Bin really like this?

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Wuling Binguo adopts cage body design, and the proportion of ultra-high strength steel in the whole body reaches 74%, and the ultra-high strength steel of 1500MPa covers 25 key protection positions of the whole car. In addition, Wuling Binguo has been built in many key positions, including the ultra-high-strength steel anti-collision beam used in the door and the full-frame sub-frame, which has greatly improved the anti-collision ability of Wuling Binguo, and can ensure the personal safety of the people inside the car even if the vehicle has an offset collision, a rollover and other accidents.

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In terms of chassis suspension, Wuling Binguo’s 410km Lingxi exclusive model has undergone a brand-new high-order adjustment of the chassis. The original rear torsion beam has been changed from an open design to a closed design, and the bearing capacity has increased by 41%, and the chassis integrity has been improved accordingly, reducing vibration transmission and improving the roll support of the vehicle. In addition, the new car has also adjusted the chassis parts such as spring, shock absorber and steering system, so that the vehicle can achieve a more comfortable driving state.

God refined battery blessing, so that you no longer have to worry about battery safety?

The battery safety of pure electric vehicles is one of the key factors that consumers are most concerned about at present, and thanks to the blessing of Wuling black technology-Shenlian battery, you are no longer worried about the battery safety of Wuling Binguo.

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The battery pack of Shenlian battery adopts the original MUST multifunctional integrated structural technology, which can effectively improve the structural strength of the battery system by more than 10%, and has the characteristics of easy disassembly and convenient maintenance, and has an ultra-high protection level of IP68. In addition, the battery core of Shenlian battery adopts the "top-asking technology" pioneered by the industry, and optimizes the design from the internal structure, solid-liquid interface and material system of the battery core, and replaces the traditional U-shaped tab with an innovative L-shaped tab, thus avoiding the risk of internal short circuit caused by the contact between the tab sinking and the pole piece in the vibration condition of vehicle application, ensuring that the battery core does not short circuit, leak, precipitate lithium and catch fire, which greatly improves the safety of the battery core.

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In addition, Wuling Binguo is also equipped with a highly integrated and high-precision intelligent battery management BMS system, and the intelligent monitoring of cloud batteries is available 7×24 hours a day, 7 days a week. Through the estimation and monitoring of voltage, battery temperature and other working conditions, it can quickly identify and give early warning, so that users can grasp the information of vehicle conditions in time.

Active and passive safety configuration upgrade to make driving more secure?

In addition to superior body strength and safe battery, the active and passive safety configuration of Wuling Binguo is also quite in place, which can make your car experience safer and more secure.

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Wuling Binguo 410km Lingxi exclusive model not only comes standard with the main and co-pilot double airbags, but also adds the front side airbags. In addition, the rear brake is also changed from disc type, and then combined with electronics, so that the braking ability of Wuling Binguo is more stable, and the thermal attenuation of continuous braking will be greatly reduced.

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In addition, the passive safety of Wuling Binguo 410km Lingxi exclusive model includes EBA brake assist, TCS traction control, uphill assist and ESC body stability control, and these safety configurations can greatly improve the safety performance of this pure electric car. In addition, automatic headlights and automatic wipers can improve the safety of driving at night and in rainy days.

Conclusion:

Previously, everyone was concerned about the outstanding performance of Wuling Bingo in terms of face value, space and battery life. However, in terms of invisible safety performance, Wuling Bingo was also very careful in terms of body strength, battery safety and active and passive safety. Since the birth of Wuling Bingo, it was for the people. What reason do you not choose such a car?

Putin pushes women into politics "Blonde" surges Russian politics.

  


  


  


  Khorkina (top), a famous gymnast, has become a member of the United Russia Party, and the Blonde Party has to look to Sharapova, a famous Russian tennis star (bottom).


  From Yeltsin, who gave a speech in a tank car, to Putin, who drove a fighter plane to inspect the front line, for many years, the Russian people never seemed to hide their desire for strong leaders. However, in Russia, where female politicians are barren as a desert, there are now a few "blondes" coming to the front desk from all directions.


  The "Blonde Party" is threatening.


  A few days ago, Russia formally established a "Blonde Party" and recruited at least 5,000 members in three weeks. The party plans to participate in the Russian presidential election in 2012, and strives to let a blonde sit on the presidential throne of the Kremlin. A spokeswoman for the Blonde Party said that even if the elected presidential candidate is not blonde, she will dye her hair blonde when she runs for the presidency.


  According to British media reports, the idea of forming "Blonde Party" originated from an Internet community forum called "Blonde Lovers Club", which often discusses many social problems faced by Russian women in a joking way. The general secretary of the Blonde Party is 39-year-old Russian economist Marina Voroshinova. When talking about the original intention of establishing the Party, she said that because there are no other political parties in China representing women’s rights, "we decided to think and deal with the problems faced by Russian women in a more serious way."


  It is reported that the "Blonde Party" is "premeditated" to snare some famous Russian blondes, with a strong momentum. Valentina Matviyenko, the female mayor of St. Petersburg, Sharapova, a famous Russian tennis star, and Ksenia Sobchak, the daughter of Putin’s mentor and Russian socialite, have all received invitations from the party. Voroshinova claims that beauty can attract more men to vote for it. The Blonde Party even wants to win over Svetlana Medvedev, Russia’s new "first lady" with blonde hair, and create a Russian version of Hillary Clinton.


  Putin pushes women into politics


  In fact, under the impetus of Putin, the Russian cabinet has been changing the once disparity between men and women. When Putin took office, Nabiulina, Vice Minister of Economic Development and Trade, was righted, and Golikova, a senior female official, was in charge of the Ministry of Health and Social Development.


  Before the Russian Duma election at the end of last year, Putin also complained about the lack of women in the United Russia Party. The result of re-election immediately satisfied his wish: several young and beautiful former athletes, including the famous gymnast Khorkina, joined the United Russia Party and were elected as members of the Duma. Svetlana Jurova, the champion of women’s 500-meter speed skating in the 2006 Winter Olympics in Turin, was even elected as the vice chairman of the State Duma.


  Relying on its own popularity and influence, the "beautiful new force" of the Russian parliament has proved that the "gender gate" in politics is slowly loosening. What attracts people’s attention is that several of them even subverted Russia’s conservative aesthetic tradition, and all of them made stunning appearances on the cover of men’s magazines and staged "naked passion".


  A strong woman in politics is in charge.


  In addition to female party leaders, ministers and parliamentarians, there are also many women in Russia’s "frontier officials". Matviyenko, the mayor of St. Petersburg, is a strong woman in politics.


  As the only female mayor in Russia, the number of media reports on matviyenko is second only to Moscow Mayor Luzhkov. Matviyenko, 57, often talks about: "People used to say that there are not enough women who are qualified to take on heavy responsibilities in government departments. In fact, we always exist."


  Matviyenko is a staunch supporter of Putin. After she became mayor, she made drastic reforms without Putin’s support. In 2005, the Russian newspaper Independent broke the news that Putin had planned to be replaced by the female mayor of the holy city because of his dissatisfaction with Fradkov, then prime minister.


  In 2007, Russia’s "Which woman do you want to see become the Russian president?" In the survey, matviyenko also won one-sided support. However, she never imagined becoming the president of Russia herself. Matviyenko said: "I think the mayor is the culmination of my political life, and my political ambitions have all been realized."


  Indeed, in the past hundred years, there has never been a female leader in Russia. But according to the current "blonde" menacing, maybe in the future, Russian politics will really put on a different kind of scenery.